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Llabnetics Pakistan
50% of first trimester pregnancy losses are due to chromosomal abnormalities
For assisted reproduction patients, 60% of first trimester pregnancy losses are due to chromosomal abnormalities
Reliable results are obtained in 99% of cases
What is POC?
The POC test analyzes fetal tissues from a miscarriage to determine if the lost pregnancy was the result of a chromosomal aneuploidy.
This test can provide you an important information about the possible causes of your patient’s miscarriage to help them to plan any future pregnancy.
Methodology
Why use POC test?
The genetic study of fetal tissue is a valuable tool to determine the cause of the miscarriage, which enables appropriate reproductive counseling for the couple.
> Results are obtained in 99% of cases.
> Results are available in 10 working days as cell culture is not required.
> 24 chromosomes are screened to identify the reason for miscarriage.
> Can be performed on twin pregnancies.
> Our test discerns between maternal and fetal tissue using DNA fingerprinting (STR Technology).
> NGS has higher resolution than a conventional karyotype.
Who should use POC test?
POC is recommended for all couples who have suffered a miscarriage, but is essential for couples who have experienced recurring spontaneous abortions and those undergoing assisted reproduction treatments.
Test limitations
This technique does not detect balanced structural chromosomal abnormalities and may not detect: low-level mosaic aneuploidy, triploid/tetraploid chromosomes, uniparental disomy, deletions or duplications under 10 Mb.